Source: http://feeds.gawker.com/~r/gizmodo/full/~3/LiL7Tpbm_dc/how-to-prevent-running-blisters
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Source: http://feedproxy.google.com/~r/GearFactor/~3/aeDfnHFbfDY/
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WASHINGTON (AP) ? Federal employee labor unions are trying to soften the blow for more than 1 million government workers who may be forced to take unpaid time off if mandatory budget cuts kick in this week.
Union leaders have been working furiously to persuade agency managers to make other cuts that won't affect employee paychecks. But if agencies do insist on furloughs, unions say they can bargain over when they take place and other terms that could help workers in financial trouble.
"We plan to exercise those rights," said Jacqueline Simon, public policy director at the American Federation of Government Employees, which represents over 650,000 workers.
More than half of the nation's 2.1 million government workers may be required to take furloughs if automatic budget cuts, known as the sequester, take effect and agencies are forced to trim budgets. Agencies also may impose hiring freezes, release temporary employees or decline to renew contract workers.
The Defense Department has said it expects to furlough 800,000 civilian workers for 22 days each, spread across more than five months, which would mean a 20 percent pay cut over that period. The Pentagon also plans to lay off as many as 46,000 temporary and contract employees.
Other federal agencies are likely to furlough several hundred thousand more workers, according to a memo last month from the Office of Management and Budget.
Unions can't stop furloughs, but they can ask to examine the agency's budget documents and make managers show there is no other way to make the cuts without furloughs.
"Our position is that the Department of Defense and every other agency actually has a lot more discretion than they're letting on and that furloughs are entirely unnecessary," Simon said. "There's certainly plenty of low-paid federal employees for whom a 20 percent pay cut means they will not be able to pay their bills."
Besides receiving no pay, a worker on furlough would not accumulate vacation time and would receive a smaller match for their government retirement account. The worker's annual salary also would be lower when calculating pension benefits.
"The impact is going to be devastating, not just on the employees who are serving unpaid furlough days, but on the American public, who depend on the services these employees provide," said Colleen Kelly, president of the National Treasury Employees Union, which represents about 150,000 workers at 31 federal agencies.
So far, Kelly's union has received only one official notice of intent to furlough workers. That came from U.S. Customs and Border Protection, which plans to furlough all 60,000 employees for up to 14 days if the sequestration goes into effect. Kelly said other agencies are looking at furloughs but have not yet specified the cuts.
"We've reached out to agencies in an effort to work with them to find ways to cut spending so that the cuts don't come on the backs of employees on furlough days," she said.
The general expectation is that employees would serve one furlough day per two-week pay period. But the union can bargain on behalf of employees who may want to serve all the days together or delay them until later in the year for personal or financial reasons.
Negotiations can also resolve whether workers can swap furlough days with other employees, or whether some workers can volunteer to serve more furlough days so others don't have to. There also may be work deadlines to consider, since some workers remain accountable to complete projects even if they cannot be at work.
The federal Office of Personnel Management, which issues guidance on how agencies carry out furloughs, declined a request for comment. But in a memo to agencies, OPM states that government officials have duty to bargain "over any negotiable impact and implementation proposals" the union may submit regarding furloughs.
In a memo to Environmental Protection Agency employees on Tuesday, acting administrator Bob Perciasepe said the agency has been taking "aggressive action" to control costs over the past few months, such as reducing contract, grant and administrative spending. But even with those savings, he said, the EPA would still have to furlough workers.
"We are working to minimize the burden on employees and their families while still enabling the agency to meet its obligations and fulfill its mission," Perciasepe said. "We are also meeting with EPA's national unions to prepare a plan for implementation."
Every agency must provide notice at least 30 days before any furlough process begins. The earliest furloughs could begin is April 1.
A few agencies have said they expect to avoid furloughs, including the Social Security Administration, Small Business Administration and Smithsonian Institution. The Veterans Affairs Department has been excluded from sequestration cuts.
"Agencies can be creative and agencies can be uncreative," Simon said. "Our position is, don't come to us because we're the easy target."
__
Follow Sam Hananel on Twitter: http://twitter.com/SamHananelAP
Source: http://news.yahoo.com/unions-aim-soften-impact-cuts-workers-080424416--finance.html
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Feb. 26, 2013 ? Though it's most often associated with disorders like diabetes, Harvard researchers have shown how the signaling pathway of insulin and insulin-like peptides plays another critical role in the body -- helping to regulate learning and memory.
In addition to showing that the insulin-like peptides play a critical role in regulating the activity of neurons involved in learning and memory, a team of researchers led by Yun Zhang, Associate Professor of Organismic and Evolutionary Biology, show that the interaction between the molecules can fine-tune how, or even if, learning takes place. Their work is described in a February 6 paper in Neuron.
"People think of insulin and diabetes, but many metabolic syndromes are associated with some types of cognitive defects and behavioral disorders, like depression or dementia," Zhang said. "That suggests that insulin and insulin-like peptides may play an important role in neural function, but it's been very difficult to nail down the underlying mechanism, because these peptides do not have to function through synapses that connect different neurons in the brain"
To get at that mechanism, Zhang and colleagues turned to an organism whose genome and nervous system are well described and highly accessible by genetics -- C. elegans.
Using genetic tools, researchers altered the small, transparent worms by removing their ability to create individual insulin-like compounds. These new "mutant" worms were then tested to see whether they would learn to avoid eating a particular type of bacteria that is known to infect the worms. Tests showed that while some worms did learn to steer clear of the bacteria, others didn't -- suggesting that removing a specific insulin-like compound halted the worms' ability to learn.
Researchers were surprised to find, however, that it wasn't just removing the molecules that could make the animals lose the ability to learn -- some peptide was found to inhibit learning.
"We hadn't predicted that we would find both positive and negative regulators from these peptides," Zhang said. "Why does the animal need this bidirectional regulation of learning? One possibility is that learning depends on context. There are certain things you want to learn -- for example, the worms in these experiments wanted to learn that they shouldn't eat this type of infectious bacteria. That's a positive regulation of the learning. But if they needed to eat, even if it is a bad food, to survive, they would need a way to suppress this type of learning."
Even more surprising for Zhang and her colleagues was evidence that the various insulin-like molecules could regulate each other.
"Many animals, including the humans, have multiple insulin-like molecules and it appears that these molecules can act like a network," she said. "Each of them may play a slightly different role in the nervous system, and they function together to coordinate the signaling related to learning and memory. By changing the way the molecules interact, the brain can fine tune learning in a host of different ways."
Going forward, Zhang said she hopes to characterize more of the insulin-like peptides as a way of better understanding how the various molecules interact, and how they act on the neural circuits for learning and memory.
Understanding how such pathways work could one day help in the development of treatment for a host of cognitive disorders, including dementia.
"The signaling pathways for insulin and insulin-like peptides are highly conserved in mammals, including the humans," Zhang said. "There is even some preliminary evidence that insulin treatment, in some cases, can improve cognitive function. That's one reason we believe that if we understand this mechanism, it will help us better understand how insulin pathways are working in the human brain."
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/HFukdteMQE0/130226162837.htm
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By Andrew Rafferty, Staff Writer, NBC News
Coast Guard officials are scratching their heads after ending a two-day search of the Northern California coast for a reportedly capsized boat that, so far, they are not sure ever existed. ??
The two-day search for the boat off the Monterey coast near San Francisco was suspended on Tuesday with no signs of debris or any indication that an incident occurred, according to a Coast Guard spokesman.
An air and sea search over a 20,000-mile area of the Pacific Ocean began Sunday evening when a man placed a distress call around 4:20 p.m. saying his 29-foot sailboat was taking on water and having problems with its electronics. Also on board were the man?s wife, 4-year-old son and a young cousin, according to the caller.
About one hour after the initial call, the family of four declared they were abandoning ship. ??
On Tuesday the Coast Guard released audio of the calls in hopes that a member of the public could identify the man?s voice. The gargled audio is difficult to make out, but officials believe the name of the boat is Charmblow.
"Coast Guard, Coast Guard, we are abandoning ship. This is the (Charmblow), we are abandoning ship," the ship?s operator said in the faint audio.
Problem is, there is no registered owner to a boat by that name, the family has yet to be identified and no one in the area has been reported missing. Officials are not ruling out that the incident may have been a hoax.
And as the Coast Guard called back the patrol boats, planes and helicopters participating in the 42-hour search, officials were turning to the public for help.
?If anyone knows someone who owns a vessel with a similar sounding name, please let us know that,? Coast Guard Chief Petty Officer Mike Lutz told NBC BayArea.
Lutz said the family did not have life rafts, but were trying to use coolers and other materials on the boat to use as a makeshift raft.
?Right now we?re asking the public if they know anyone, a friend a relative a neighbor who went out and hasn?t come back that they please call the Coast Guard,? said Lutz.
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DID YOU KNOW? That while all states have motor vehicle title laws, only about two-thirds have title laws for vessels? There is a bill, SB 1117, the Virginia Uniform Certificate of Title for Watercraft Act, that is currently making its way through the Virginia Legislature. The passage of this legislation will create a uniform system of boat titling that will be recognized nationwide and by the United States Coast Guard. The benefits to the consumer will include protection for prospective boat buyers by clearly labeling the titles of damaged vessels, preventing the sale of stolen boats and provide a clear chain of ownership.SELLING THE SEAWORTHY POLICY "Consequential Damage Coverage" is featured on all of the Seaworthy Charter, Yacht and SuperYacht Polices. This covers immediate consequential property damage resulting from any fire, explosion, grounding, sinking, demasting, collision or stranding. If wear and tear on a cracked hose causes a boat to sink at the dock, many providers won't cover the resulting damage to the boat (or the cost to refloat it if it sinks) because the initial cause, the deteriorated (cracked) hose isn't covered. This could cost a boat owner significant out of pocket expense unless their insurance policy covers the "consequential" damage. A real PLUS for the Seaworthy customer!Posted Tuesday, February 26 2013 11:33 AM |
NOTICE: This blog and website are made available by the publisher for educational and informational purposes only. It is not be used as a substitute for competent insurance, legal, or tax advice from a licensed professional in your state. By using this blog site you understand that there is no broker client relationship between you and the blog and website publisher.
Source: http://www.caseyinsurancegroup.com/blog/boat_titles_and_seaworthy_policies.aspx
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VATICAN CITY - The Vatican has answered some of the outstanding questions about Pope Benedict XVI's future once he's retired, saying he'll be known as "emeritus pope," and continue to wear a white cassock.
The Vatican spokesman the Rev. Federico Lombardi said Tuesday that Benedict himself made the decisions.
The pope's title and what he would wear has been a major question ever since Benedict stunned the world and announced he would resign on Thursday. While he will no longer wear his trademark red shoes, Benedict has taken a liking to a pair of hand-crafted brown loafers made for him by artisans in Leon, Mexico and presented to him during his 2012 visit. He will wear them in retirement.
Source: http://news.yahoo.com/vatican-retired-pope-benedict-xvi-called-emeritus-pope-121411564.html
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The modern age of computers and digital applications is unhealthy for eyes. Since most of us do not maintain a special care routine for eyes and work all the time, the eyes are always under constant strain. The only time we give rest to our eyes is when we are asleep.
But this is not enough. You need to take out time to maintain a special routine for eyes. Focus on strengthening your vision.
Yoga is the best way you can take care of your eyes. There are many Yogic eye exercises that you can practise to maintain good health for your eyes. These exercises are easy to do. Most of these exercises can be easily performed at any time of the day regardless of where you are! Here are some effective Yoga exercises to help you take good care of eyes:
1. Close your eyes as tight as possible. Hold on for around 5 seconds. Open them, and close them again. repeat the exercise about six times.
2. In case, you sit in front of the computer screen for long hours, it is important that you get up every half an hour and move around a bit. Fetch yourself a glass of water. The idea is to give your eyes some break. A 2 minute break is enough to refresh the eyes.
3. Shut your eyes. Now roll your eyeballs around for a minute. Repeat.
4. Rub your palms together. Now gently cup them over your closed eyes for around a minute. This is an effective exercise and often referred to as palming. The exercise is extremely beneficial for the eyes. Understand that eyes need darkness to rejuvenate themselves. Palming is the best way to ensure adequate darkness to eyes.
5. Imagine that there is a huge clock in front of you. Now look at the number 12 for around 10 seconds. Gradually move your gaze down to 6. Repeat the exercise for around 10 times, rapidly. Now move your eyes horizontally, in the 3-9 position. Also the eyes diagonally in 2-7 and 10-4 positions respectively.
6. Sambhavi mudra is known to be the best exercise for eyes. You need to look up to the position in the middle of your eyebrows. Make sure you hold on for a few seconds and then move your gaze downwards, towards your nose.
7. Blink is important to lubricate the eyes. So make a conscious effort to blink more.
Source: http://www.foodfitnesslifelove.com/yoga/yoga-for-eyes-incredible-health-benefits-of-yoga/
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There are numerous function rooms North Sydney venues to choose from like galleries, hotels, conference centres, exhibition centres, reception centres etc. They differ in size as well as service offered and depending on your budget, need of space and other services you can choose one thats right for you. The first criteria to be considered while choosing the venue is the reason or type of function, based on this you will be able to determine which kind of function room will be ideal. Like for example a corporate meeting of about 10 people would look quite inapprop0riate if held in an art gallery which has a capacity of about 100 people. The participants would feel lost in the empty space not to mention the difficulty one would have in arranging all the technical equipments needed to host a corporate meeting successfully.
The second criteria would be the amenities and services needed. Each event type needs a different set of amenities and services. A wedding reception would need a dance floor, bridal room, formal table settings, floral and other decorative arrangements and elaborate catering facilities including wedding cake etc, a corporate meeting would require audio and visual equipment, flip charts and writing boards, computers and internet facilities and a formal theatre-style or round-table seating arrangement, an art exhibition may need the right kind of spot-lighting on the paintings to highlight its beauty amongst various other arrangements including temperature and humidity control. The different venues are geared to serve different clientele and all you need to do is discuss your event type and they can guide you through to the right setting.
Once you have decided on the type of function rooms North Sydney to hire you must go through their floor plan. Most of these event managers are professionals and know their job pretty well however your needs and expectations will definitely be different from others and to make sure you are fully satisfied with the arrangements. Depending on the floor plan there are different types of seating arrangements to choose from theatre, classroom and U-shape. Similarly there are different floor plans for the festive event too like boardroom, cabaret, banquet and cocktail. It would be a good idea to hold business and boardroom meetings in rooms that have maximum natural light flowing in like glass windows from floor to ceiling, this should help keep the participants awake and fresh all day long. Also dont forget to ask for the coffee / tea vending machines as most office-goers are coffee addicts and it helps them to concentrate on the meeting better.
About the Author:
Jasper Mason is a travel author. He pen articles related to party and conference venues and share his experience about function rooms North Sydney. He appreciate hotels in Sydney for stay when you visit Australia.
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Are there months that are better to go to Tortola and or Jost? Less wave action? We're up for anything, just want to have a little adventure this weekend.
Source: http://www.vimovingcenter.com/talk/read.php?4,198269,198269
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Feb. 25, 2013 ? In a recently published study in the journal Biological Trace Element Research, Arizona State University researchers report that children with autism had higher levels of several toxic metals in their blood and urine compared to typical children. The study involved 55 children with autism ages 5-16 years compared to 44 controls of similar age and gender.
The autism group had significantly higher levels of lead in their red blood cells (+41 percent) and significantly higher urinary levels of lead (+74 percent), thallium (+77 percent), tin (+115 percent), and tungsten (+44 percent). Lead, thallium, tin, and tungsten are toxic metals that can impair brain development and function, and also interfere with the normal functioning of other body organs and systems.
A statistical analysis was conducted to determine if the levels of toxic metals were associated with autism severity, using three different scales of autism severity. It was found that 38-47 percent of the variation of autism severity was associated with the level of several toxic metals, with cadmium and mercury being the most strongly associated.
In the paper about the study, the authors state "We hypothesize that reducing early exposure to toxic metals may help ameliorate symptoms of autism, and treatment to remove toxic metals may reduce symptoms of autism; these hypotheses need further exploration, as there is a growing body of research to support it."
The study was led by James Adams, a President's Professor in the School for Engineering of Matter, Transport and Energy, one of ASU's Ira A. Fulton Schools of Engineering. He directs the ASU Autism/Asperger's Research Program.
Adams previously published a study on the use of DMSA, an FDA-approved medication for removing toxic metals. The open-label study found that DMSA was generally safe and effective at removing some toxic metals. It also found that DMSA therapy improved some symptoms of autism. The biggest improvement was for children with the highest levels of toxic metals in their urine.
Overall, children with autism have higher average levels of several toxic metals, and levels of several toxic metals are strongly associated with variations in the severity of autism for all three of the autism severity scales investigated.
The study was funded by the Autism Research Institute and the Legacy Foundation.
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The above story is reprinted from materials provided by Arizona State University.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/N71YjoJQ-TM/130225162231.htm
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BEIRUT (AP) ? Syria said Monday it is prepared to hold talks with the armed rebels bent on overthrowing President Bashar Assad, the clearest signal yet that the regime is growing increasingly nervous about its long-term prospects to hold onto power as opposition fighters make slow but persistent headway in the civil war.
The offer, by Syrian Foreign Minister Walid al-Moallem during a visit to Moscow, came hours before residents of Damascus and state-run TV reported a huge explosion and a series of smaller blasts in the capital, followed by heavy gunfire.
State-run news agency SANA said there were multiple casualties from the explosion, which it said was a suicide car bombing.
The proposal marked the first time that a high-ranking regime official has stated publicly that Damascus would be willing to meet with the armed opposition. But al-Moallem did not spell out whether rebels would first have to lay down their weapons before negotiations could begin ? a crucial sticking point in the past.
The regime's proposal is unlikely to lead to talks. The rebels battling the Syrian military have vowed to stop at nothing less than Assad's downfall and are unlikely to agree to sit down with a leader they accuse of mass atrocities.
But the timing of the proposal suggests the regime is warming to the idea of a settlement as it struggles to hold territory and claw back ground it has lost to the rebels in the nearly 2-year-old conflict.
Opposition fighters have scored several tactical victories in recent weeks, capturing the nation's largest hydroelectric dam and overtaking airbases in the northeast. In Damascus, they have advanced from their strongholds in the suburbs into neighborhoods in the northeast and southern rim of the capital, while peppering the center of the city with mortar rounds for days.
Monday night's explosion struck about 800 yards (meters) from Abbasid Square, a landmark plaza in central Damascus. It was followed by several other smaller blast thought to be mortar shells landing in various districts of the capital. The blasts and subsequent gunfire caused panic among residents who hid in their apartments.
On Thursday, a car bomb near the ruling Baath Party headquarters in Damascus killed at least 53 people, according to state media.
While the momentum appears to be shifting in the rebels' direction, the regime's grip on Damascus remains firm, and Assad's fall is far from imminent.
Still, Monday's offer to negotiate with the armed opposition ? those whom Assad referred to only in January as "murderous criminals" and refused to talk with ? reflects the regime's realization that in the long run, its chances of keeping its grip on power are slim.
Asked about al-Moallem's remarks, U.S. State Department spokesman Patrick Ventrell said the offer of talks was a positive step "in the context of them raining Scuds down on their own civilians." But he expressed caution about the seriousness of the offer.
"I don't know their motivations, other than to say they continue to rain down horrific attacks on their own people," Ventrell told reporters in Washington. "So that speaks pretty loudly and clearly."
If the Assad regime is serious, he said, it should inform the U.N. peace envoy, Lakhdar Brahimi of its readiness for talks. Ventrell said the regime hasn't done that yet.
Andrew Tabler, a fellow at the Washington Institute, said called the offer "a sign of weakness."
"I think everybody knows, including Bashar Assad, that they (the regime) can't hang onto the whole country," Tabler said.
Mustafa Alani, an analyst with the Gulf Research Center in Geneva, said the regime has "reached the conclusion that they are heading toward a major defeat eventually, and this is the right time to negotiate."
"They are not losing miles every day, but they are losing substantial ground every day. So the regime is not genuine (in its offer) because it has changed, it's genuine because it is responding to a major shift in the balance of power on the ground," he added.
Alani cautioned, however, that the regime is also eager to keep the idea of talks alive in order to forestall any Western decision on arming the rebels. As long as the possibility of negotiations is still on the table, the U.S. and the European Union ? which have so far provided only non-lethal aid ? will be reluctant to open the flood gates on weapons for the opposition, he said.
"The whole regime tactic is to delay supplying arms, to buy time," Alani said. "The regime can show good will. Whether they're a viable partner or not is a different story."
It's also unclear who exactly the regime would sit across from at the negotiating table.
The dozens of armed groups across Syria fall under no unified command and do not answer to the Syrian National Council, an umbrella group of opposition parties that the West recognizes as the legitimate representative of the Syrian people.
At least one group offered a lukewarm response Monday to al-Moallem's proposal.
The head of one group, Free Syrian Army chief Gen. Salim Idriss, said he is "ready to take part in dialogue within specific frameworks," but then rattled off conditions that the regime has rejected in the past.
"There needs to be a clear decision on the resignation of the head of the criminal gang, Bashar Assad, and for those who participated in the killing of the Syrian people to be put on trial," Idriss told pan-Arab broadcaster Al-Arabiya TV.
He said the government must agree to stop all kinds of violence and to hand over power, saying that "as rebels, this is our bottom line."
Syria's 23-month-old conflict, which has killed more than 70,000 people and destroyed many of the country's cities, has repeatedly confounded international efforts to bring the parties together to end the bloodshed. Russia, a close ally of Assad and his regime's chief international advocate, offered Feb. 20, in concert with the Arab League, to broker talks between the rebels and the government.
With the proposal, which the Kremlin would be unlikely to float publicly without first securing Damascus' word that it would indeed take part, Moscow ratcheted up the pressure on Syria to talk to the opposition.
Russia has shielded Assad's government from U.N. action and kept shipping weapons to the military, but it is growing increasingly difficult to protect the regime as the violence grinds on.
Russian Foreign Minister Sergey Lavrov repeated his call Monday for Syria to negotiate with the opposition, saying before meeting al-Moallem that "the situation in Syria is at a crossroads now." He also warned that further fighting could lead to "the breakup of the Syrian state."
Past government offers for talks with the opposition have included a host of conditions, such as demanding that the rebels first lay down their arms. Those proposals have been swiftly rejected by both activists outside Syria and rebels on the ground.
Both sides in the conflict in recent weeks have floated offers and counteroffers to hold talks on the crisis.
In a speech in January, Assad offered to lead a national dialogue to end the bloodshed, but said he would not talk with the armed opposition and vowed to keep fighting. The opposition rejected the proposal.
This month, the leader of the Syrian National Coalition, the umbrella group for opposition parties, said he would be open to discussions with the regime that could pave the way for Assad's departure, but that the government must first release tens of thousands of detainees. The government refused, and even members within the coalition balked at the idea of talks.
Speaking to reporters Monday in Cairo, SNC chief Mouaz al-Khatib accused the regime of procrastinating and said it had derailed his dialogue offer by not responding to the coalition's conditions.
"We are always open to initiatives that stop the killing and destruction, but the regime rejected the simplest of humanitarian conditions. We have asked that the regime start by releasing women prisoners and there was no response," he said. "This regime must understand that the Syrian people do not want it anymore."
The coalition also finds itself at odds with its Western backers, and has said it will boycott a conference in Rome that is to help drum up financial and political support for the opposition. The SNC suspended its participation in the Rome meeting because of the indifference of the West and the coalition's Arab allies over the regime's attacks on the Syrian people in Aleppo and other cities.
Walid al-Bunni, a spokesman for the Coalition, said later Monday that the group has reversed its decision following a phone call between al-Khatib and U.S. Secretary of State John Kerry.
Al-Bunni told Al-Arabiya TV the decision was made based on guarantees al-Khatib heard from western diplomats that the conference would be different this time. He did not elaborate.
Kerry on Monday urged rebel leaders not to skip the meeting and insisted that more help is on the way.
Kerry made a public plea at a joint news conference with British Foreign Secretary William Hague and also called al-Khatib, leader of the Syrian Opposition Council, "to encourage him to come to Rome," a senior U.S. official said. The official spoke on condition of anonymity because he wasn't authorized to speak publicly on the matter.
Meanwhile, the fighting inside Syria rages on.
The Syrian Observatory for Human Rights activist group reported heavy clashes Monday near a police academy in Khan al-Asal just outside Aleppo.
Rebels backed by captured tanks launched an offensive on the facility Sunday. Observatory director Rami Abdul-Rahman said at least 13 rebels and five regime troops were killed.
In another part of Aleppo, rebels downed a military helicopter near the Mennegh airport, where there have been fierce clashes for months.
A video posted online by activists showed a missile being fired, a trail of white smoke and the aircraft going up in flames. Voices in the background shouted, "God is great!" as a man raised both hands in celebration.
The video appeared to be authentic and corresponded to other AP reporting.
___
Associated Press writers Nataliya Vasilyeva in Moscow, Albert Aji in Damascus, Zeina Karam in Beirut, Matthew Lee in London, Bradley Klapper in Washington and Geir Moulson in Berlin contributed to this report.
Source: http://news.yahoo.com/syria-says-prepared-talk-armed-rebels-195253563.html
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>>> sweeping automatic budget cuts set to take effect in just four days unless lawmakers reach a deal. peter alexander takes a look at how it will affect everything from air travel to the food we eat. peter, good morning to you.
>> reporter: yeah, savannah, that's all true this morning the white house is picking up the pace of its pr offensive, rolling out reports for each of the country states and how they will be affected by its automatic budget cuts. the president will speak to the governors here in washington for their winter meetings . republic republicans also don't like these cuts, but they accuse the president of failing to lead and ultimately it's you who could be affected. at the shipyard in norfolk, virginia, 1,600 letters with possible pink slips are already in the mail while they're waiting for washington to act. still with the clock ticking down, no signs of progress, but plenty of dire warnings from the administration about the potential impact of the so-called sequester. fewer fbi agents on the job. kids kicked out of child care programs. even meat shortages that could jack up prices with fewer inspectors working.
>> if we don't have inspection, we're not going to be working so i don't need the employees here.
>> reporter: fewer tsa agents, fewer air traffic controller , meaning more time on the tarmac. states would be hard hit, too, releasing these new figures overnight. in california, 9,600 low-income students could lose their college financial aid , in florida, nearly $4 million could be slashed to provide meals for needy seniors and in texas, nearly 10,000 fewer children will receive vaccines for diseases like whooping cough and the flu. just in time for spring, national parks like yosemite will see their services cut, 700,000 defense department workers to take one day off a week, a 20% pay cut. near quantico marine base in virginia, it's already breeding anxiety.
>> people are hunkered down, really afraid to spend any kind of money.
>> reporter: both sides seem to agree these cuts will go into effect at the end of this week. there's also at least some good news. most of the layoffs and furloughs won't actually take place until a month from now.
>> maybe they will sort it out at some point. peter alexander at the white house , thank you very much.
Source: http://video.today.msnbc.msn.com/today/50939215/
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By: Tia Ghose, LiveScience Staff Writer
Published: 02/25/2013 03:05 PM EST on LiveScience
Brain cells can live at least twice as long as the organisms in which they reside, according to new research.
The study, published today (Feb. 25) in the journal Proceedings of the National Academy of Sciences, found that mouse neurons, or brain cells, implanted into rats can survive with the rats into old age, twice as long as the life span of the original mice.
The findings are good news for life extension enthusiasts.
"We are slowly but continuously prolonging the life of humans," said study co-author Dr. Lorenzo Magrassi, a neurosurgeon at the University of Pavia in Italy.
So if the human life span could be stretched to 160 years, "then you are not going to lose your neurons, because your neurons do not have a fixed lifetime."
Long-lived cells
While most of the cells in the human body are being constantly replaced, humans are born with almost all the neurons they will ever have. [10 Odd Facts About the Brain]
Magrassi and his colleagues wanted to know whether neurons could outlive the organisms in which they live (barring degenerative diseases like Alzheimer's).
To do so, the researchers took neurons from mice and implanted them into the brains of about 60 rat fetuses.
The team then let the rats live their entire lives, euthanizing them when they were moribund and unlikely to survive for more than two days, and then inspected their brains. The life span of the mice was only about 18 months, while the rats typically lived twice as long.
The rats were found to be completely normal (though not any smarter), without any signs of neurological problems at the end of their lives.
And the neurons that had been transplanted from mice were still alive when the rats died. That means it's possible the cells could have survived even longer if they were transplanted into a longer-lived species.
Life extension
The findings suggest that our brain cells won't fail before our bodies do.
"Think what a terrible thing it could be if you survive your own brain," Magrassi told LiveScience.
While the findings were done in rats, not humans, they could also have implications for neuronal transplants that could be used for degenerative diseases like Alzheimer's disease or Parkinson's disease, Magrassi said.
But just because brain cells may be able to live indefinitely doesn't mean humans could live forever.
Aging is dependent on more than the life span of all the individual parts in the body, and scientists still don't understand exactly what causes people to age, Magrassi said.
Follow LiveScience on Twitter @livescience. We're also on Facebook?& Google+.?
Copyright 2013 LiveScience, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.Also on HuffPost:
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Source: http://www.huffingtonpost.com/2013/02/26/mouse-brain-cells-life-span-extension_n_2762163.html
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Austin Leads Charge as Drake Men's Track and Field Claims Two Titles on Final Day of 2013 MVC Indoor Championships
Courtesy: Drake Athletics
Release: 02/24/2013
CEDAR FALLS, Iowa - Drake University junior Brogan Austin (Boone, Iowa) defended his title in the 5,000 meters Sunday with a time of 14:21.36 to complete action at the 2013 MVC Indoor Track and Field Championships at the UNI Dome.
"Today was an amazing day for the Bulldogs," Drake head coach Natasha Kaiser-Brown said. "With Ryan Cook finishing second in the high jump, Brett [Wright] pulling out a third-place finish in the 400 meters, Brogan [Austin] winning the 5,000 meters and then the 4x400-meter relay capping off the day with a victory was awesome."
Spurred by a disappointing performance in the 3,000 meters on Saturday, Austin dominated the field in the race, coming in a full 11 seconds ahead of the next finisher, John Mascari of Indiana State. He was just 26 one-hundreths of a second shy of his personal best he set in winning last year's race.
"Brogan was disappointed with his 3,000-meter finish on the first day of the championships," Drake distance coach Dan Hostager said. "He really tried to put the race away early and it paid off as he nearly set the MVC meet record. Both races had extremely competitive fields so it will provide some great momentum heading into the outdoor season."
The Bulldogs second title of the day came in the 4x400-meter relay. The Drake team of Scott Goad (Dixon, Ill.), Travis Marsh (Ankeny, Iowa), Ian Wells (Champaign, Ill.), and Brett Wright (Longmont, Colo.) sprinted to a time of 3:18.99 for the victory.
Marsh was also sixth in the finals of the 200 meters, crossing the line in 22.82 and eighth in the 60-meter hurdles in 8.45.
Wright made the podium in the 400 meters, finishing third in 49.30. Wells' time of 50.06 was seventh in the same final.
A group of freshmen had good showings in their first MVC competition. Ryan Cook (Colorado Springs, Colo.) was second in the high jump, soaring to a height of 6-8 on his first attempt, a personal best. Goad cleared a height of 6-4 for 12th place.
Freshman Jim Saxton (La Crosse, Wis.), the only freshman in the 800-meter field, was seventh in 1:58.00. Teammate senior Charlie Lapham (Golden Valley, Minn.) was eighth in the event in 2:03.93.
Lapham was fifth in the mile in 4:17.41. Junior Ryan Flynn (Bettendorf, Iowa) was 15th in 4:33.85.
Junior Alex Kaster (Omaha, Neb.) was seventh in the triple jump with a distance of 46-4 while senior Dan Karys (Bartlett, Ill.) was directly behind him in eighth with a jump of 46-1.50. Freshman Sean Buczek (Crystal Lake, Ill.) had the 13th best jump in 44-5.25.
The team finished fifth in the team standings with 70 points. Indiana State won the meet with 164.50 points.
The meet marks the final time the team will compete during the indoor season. Individuals will have a chance to qualify for the NCAA Championships on March 8-9 next week at three different 'last chance' meets.
2013 MVC Indoor Championships
Team Results
1.????
Indiana
State, 164.50
2.????
Wichita
State, 137
3.????
Northern
Iowa, 121
3.???? Southern Illinois,
121
5.???? Drake, 70
6.???? Illinois State,
43.50
2013 MVC Indoor Championships
Drake Men's Results
200 Meters
6. Travis
Marsh, 22.82
400 Meters
3. Brett
Wright, 49.30
7. Ian
Wells, 50.06
800 Meters
7. Jim
Saxton, 1:58.00
8. Charlie
Lapham, 2:03.93
Mile Run
5. Charlie
Lapham, 4:17.41
15. Ryan
Flynn, 4:33.85
5,000 Meters
1. Brogan
Austin, 14:21.36
60-Meter Hurdles
8. Travis
Marsh, 8.45
4x400 Meter Relay
1. Drake
'A', 3:18.99
Relay:
Scott Goad, Travis Marsh, Ian Wells, Brett Wright
High Jump
2. Ryan
Cook, 6-8.00
12. Scott
Goad, 6-4.00
Triple Jump
7. Alex
Kaster, 46-4.00
8. Dan
Karys, 46-1.50
13. Sean
Buczek, 44-5.25
Source: http://www.godrakebulldogs.com/ViewArticle.dbml?DB_OEM_ID=15700&ATCLID=206498266
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FILE - In the Dec. 15, 2012, Illinois Democratic U.S. Congressional hopeful Debbie Halvorson speaks during a candidate presentation at the 2nd Congressional District slating meeting in South Holland, Ill. Candidates for former Congressman Jesse Jackson Jr.'s 2nd congressional seat made their final push for votes Monday Feb. 25, 2013, ahead of tomorrow's high-stakes primary. Turnout is expected to be paltry despite the lurid headlines surrounding the disgraced Chicago Democrat and millions in outside super PAC money driven largely by the guns debate. (AP Photo/John Smierciak, File)
FILE - In the Dec. 15, 2012, Illinois Democratic U.S. Congressional hopeful Debbie Halvorson speaks during a candidate presentation at the 2nd Congressional District slating meeting in South Holland, Ill. Candidates for former Congressman Jesse Jackson Jr.'s 2nd congressional seat made their final push for votes Monday Feb. 25, 2013, ahead of tomorrow's high-stakes primary. Turnout is expected to be paltry despite the lurid headlines surrounding the disgraced Chicago Democrat and millions in outside super PAC money driven largely by the guns debate. (AP Photo/John Smierciak, File)
FILE - In this Dec. 15, 2012 file photo, Illinois Democratic U.S. Congressional hopeful Robin Kelly speaks during a candidate presentation at the 2nd Congressional District Slating Meeting in South Holland, Ill. Candidates for former Congressman Jesse Jackson Jr.'s 2nd congressional seat made their final push for votes Monday Feb. 25, 2013, ahead of tomorrow's high-stakes primary. Turnout is expected to be paltry despite the lurid headlines surrounding the disgraced Chicago Democrat and millions in outside super PAC money driven largely by the guns debate. (AP Photo/John Smierciak, File)
FILE - In this Feb. 7, 2013 file photo, Illinois Democratic U.S. Congressional hopeful Anthony Beale, speaks at a news conference in Chicago. Candidates for former Congressman Jesse Jackson Jr.'s 2nd congressional seat made their final push for votes Monday Feb. 25, 2013, ahead of tomorrow's high-stakes primary. Turnout is expected to be paltry despite the lurid headlines surrounding the disgraced Chicago Democrat and millions in outside super PAC money driven largely by the guns debate. (AP Photo/M. Spencer Green, File)
CHICAGO (AP) ? The primary contest to replace disgraced former U.S. Rep. Jesse Jackson was in the hands of Chicago-area voters Tuesday, just three months after his resignation and an intense period of campaigning by more than a dozen candidates.
The front-runners ? former state Rep. Robin Kelly, former U.S. Rep. Debbie Halvorson and Chicago Alderman Anthony Beale ? planned Election Day stops at train stations and restaurants in the district that spans Chicago's South Side, south suburbs and some rural areas. They were among 14 Democrats and four Republicans in the special primary, but the Democratic winner was expected to sail through the April 9 general election because of the heavily Democratic region.
Beale planned to vote at a school in Chicago, Halvorson was set to cast a ballot at a suburban community center and Kelly voted early.
Voters haven't seen an open primary since 1995, when Jackson first won office.
Turnout at the polls was expected to be low, and candidates and election officials braced for a possible winter storm that could dump up to six inches of snow on the region and complicate Tuesday's logistics. Election officials said they were in communication with streets and sanitation workers about making sure pathways to polls were kept clear.
In Chicago, fewer than 2,800 voters, or roughly 2 percent or registered voters in the district, cast early ballots. In suburban Cook County ? the bulk of the district's voting population ? it was nearly 2 percent. The last time the Chicago area had a special primary election for Congress was 2009 after Rahm Emanuel left his seat to take a job as White House chief of staff. Roughly 18 percent of registered voters in the district spanning North Side neighborhoods voted. In suburban Cook County, the percentage was far lower.
Guns and ethics were on the minds of voters, and both were main issues on the campaign trail, particularly as Jackson's legal saga played out in federal court. He pleaded guilty to illegally spending $750,000 in campaign money on personal items and faces prison time. The son of the civil rights leader is the third consecutive congressman from the district to leave office under an ethical or legal cloud.
Still, gun control became the top issue on the campaign trail, including at candidate forums and television ads.
Independence USA, the super PAC of New York City Mayor Michael Bloomberg, poured more than $2 million into the race for anti-gun ads in support of Kelly and against Halvorson, a former state lawmaker and one-term congresswoman. Kelly supports a ban, but Halvorson does not.
"Gun control, we need it," said retiree Angela Craig, an undecided Chicago voter. She had supported Jackson in the past but didn't feel like she got enough time to weigh the candidates.
Jackson resigned in November after a months-long medical leave. He pleaded guilty early this month to charges that he misspent $750,000 in campaign money on lavish personal items, including a Rolex watch and furs. His departure created a rare opening in the district.
___
Sophia Tareen can be reached at http://twitter.com/sophiatareen
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Intel is no longer willing to ignore such a large segment of the market and that is why the company is investing most of their time on mobile phones computing ? in particular developing next generation Intel chips for smartphones, alliance with leading smartphone players and acquiring and investing in software services for mobile apps.
At Mobile World Congress this week, many, including Intel, have taken the opportunity to reintroduce themselves to the world, with a fresh take on the mobile industry. ?A year has made all the difference for Intel in particular, as the chipmaker has a significantly broader line up of new chips and industry relationships to announce at MWC 2013.
The Atom processor remains a central focus for Intel, unveiling its first dual-core chip for smartphones, the Clover Trail+. ?Energy efficiency is a key improvement for Clover Trail +, as Intel?s chips have proven power-hungry in the past. ?And while Intel?s latest Atom chip comes with worthy specs, including an Intel graphics media accelerator engine with a graphics core supporting up to 533MHz with boost mode, rivals like ARM and Qualcomm have already moved on to the quad-core chipset (though Intel would say more cores doesn?t make a better chip). ?Intel?s also behind on LTE support, an important feature in today?s data-hungry mobile world.
Intel certainly has big plans for catching up in the smartphone space, but the chipmaker is exploring several avenues in the mobile market at large. ?The diversified approach should help Intel survive the transition to a post-PC era, where mobility and Services are key. ?Here are some of the opportunities Intel has on its plate:
.
According to the latest report from Berg Insight, the number of mobile apps downloaded across all major platforms will reach 108 billion in 2017, and the revenue market from applications, including both direct revenues (when you pay for an app) and in-app ad revenues, will reach $8.4 billion with a compound annual growth rate (CAGR) of 17% between 2012 and 2017. ?That?s a hefty market to tap as more businesses rely on apps to interface with consumers. ?The significant growth here has enabled a new economy around the developer community, which will need an array of services to support the creation,?management?and distribution of mobile apps.
appMobi has more than 130,000 active developers working on mobile and desktop applications using HTML5 as of Oct 2012. This large bunch will help Intel enhance its presence in web tools by establishing new frameworks for traditional web applications, games and mobile applications. Intel could use these to enhance its own mobile App Catalog as well.
The main objective of appMobi as a cloud platform is towards the development of browser applications that provide features such as analysis of user behavior, touch-to-buy, or certain authentications. Its?JavaScript jqMobi framework is a development code that is compatible to develop Android apps, iOS or BlackBerry OS apps. Intel wants to incorporate the acquired technologies into its own development environment. It will help Intel pursue developers to create cross-platform apps that will work in any environment on any device and (most importantly) any computer chip. Intel is also hoping that many smartphone manufacturers will therefore rely on Intel?s technology at the software level.
.
To be fair, Intel has not completely missed the mobile boat. The company is heading towards a device-agnostic future with enough hardware and processor options, along with the right software offerings in an effort to move beyond the PC market to data centers, mobile and cloud computing sectors.
Image: Intel
The 4th generation Intel Core processor family and new line of low-power processors will usher in an era of unprecedented innovation in mobile computing. The new chip will bring faster, thinner, lighter, cooler, more secure systems with built-in graphics to mainstream, an area where ARM chip is currently leading.
The company has demonstrated interesting insight given its roadmap for its range of processors, targeting areas like automobile infotainment, home automation systems, handheld devices and tablets. ?While 64% of Intel?s revenues are still derived from the PC market, the number is dropping and the chipmaker, known for its?incessant?R&D, is preparing for a new future.
McAfee, the acquired Intel Company, has become profitable in the last quarter due to the software and services and contributed over $1 billion in revenue. Its data center group is inching closer to PC client group that clocked 22% year-on-year growth.
Hyperscale computing and software-led infrastructure are two areas that Intel has also explored seriously. The company has invested $20 million cash in Big Switch Networks, an early player in software-defined networking (SDN).
Intel is also hoping to find growth in the auto industry by getting carmakers to use its technology. Partnerships with Toyota and General Motors can help Intel speed up development of these technologies. Intel?s Connected Car Fund will invest in next-generation in-car technology, advanced driver assistance technology with speech and gesture recognition. The company has also invested heavily in WiMAX, betting that it would become the standard for mobile phones operating on 4G. But unfortunately, LTE is set as the new 4G standard by telecom industries ? ? leaving Intel?s investment in this case out in the cold.
Intel?s new processor ? fourth-generation Haswell processor ? is the answer to the micro server market, with its longer life and faster speeds. In the long run, Intel is targeting the $200-$500 mobile market segment because that?s where a lot of the growth is in emerging market like China, India and Brazil. The acquisition of Infineon Technologies? wireless chip business in 2011 and investing in new mobile players in introducing Intel powered mobile devices is an indication in that direction.
Source: http://siliconangle.com/blog/2013/02/25/does-intel-have-any-mobile-growth-opportunities-left/
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Feb. 22, 2013 ? Researchers at UCLA report that they have refined a method they previously developed for capturing and analyzing cancer cells that break away from patients' tumors and circulate in the blood. With the improvements to their device, which uses a Velcro-like nanoscale technology, they can now detect and isolate single cancer cells from patient blood samples for analysis.
Circulating tumor cells, or CTCs, play a crucial role in cancer metastasis, spreading from tumors to other parts of the body, where they form new tumors. When these cells are isolated from the blood early on, they can provide doctors with critical information about the type of cancer a patient has, the characteristics of the individual cancer and the potential progression of the disease. Doctors can also tell from these cells how to tailor a personalized treatment to a specific patient.
In recent years, a UCLA research team led by Hsian-Rong Tseng, an associate professor of molecular and medical pharmacology at the Crump Institute for Molecular Imaging and a member of both the California NanoSystems Institute at UCLA and UCLA's Jonsson Comprehensive Cancer Center, has developed a "NanoVelcro" chip. When blood is passed through the chip, extremely small "hairs" -- nanoscale wires or fibers coated with protein antibodies that match proteins on the surface of cancer cells -- act like Velcro, traping CTCs and isolating them for analysis.
CTCs trapped by the chip also act as a "liquid biopsy" of the tumor, providing convenient access to tumor cells and earlier information about potentially fatal metastases.
Histopathology -- the study of the microscopic structure of biopsy samples -- is currently considered the gold standard for determining tumor status, but in the early stages of metastasis, it is often difficult to identify a biopsy site. By being able to extract viable CTCs from the blood with the NanoVelcro chip, however, doctors can perform a detailed analysis of the cancer type and the various genetic characteristics of a patient's specific cancer.
Improving the NanoVelcro device
Tseng's team now reports that they have improved the NanoVelcro chip by replacing its original non-transparent silicon nanowire substrate inside with a new type of transparent polymer nanofiber-deposited substrate, allowing the device's nanowires to better "grab" cancer cells as blood passes by them.
Tseng and his colleagues were able to pick single CTCs immobilized on the new transparent substrate by using a miniaturized laser beam knife, a technique called laser micro-dissection, or LMD.
The researchers' paper on their improvement to the chip was published online Feb. 22 in the peer-reviewed journal Angewandte Chemie and is featured on the cover of the journal's March 2013 print issue.
"This paper summarizes a major milestone in the continuous development of NanoVelcro assays pioneered by our research group," Tseng said. "We now can not only capture cancer cells from blood with high efficiency but also hand-pick single CTCs for in-depth characterization to provide crucial information that helps doctors make better decisions."
Testing the improvements on melanoma
Using the new assay on patients' blood containing circulating melanoma cells (CMCs), Tseng's team was able to isolate and preserve single CMCs. Melanoma is a deadly type of skin cancer that is prone to spreading quickly throughout the body. The ability to capture and preserve single CMCs allows doctors to analyze melanoma cells' DNA structure, determine the genetic characteristics of the patient's cancer and confirm that the circulating cells remain genetically similar to the tumor they came from.
The preservation of single captured CMCs in this proof-of-concept study also allowed researchers to conduct an analysis -- called single-cell genotyping -- to find within the cell a specific target (BRAF V600E) for a drug called vemurafenib. BRAF V600E is a mutation in the BRAF protein that appears in approximately 60 percent of melanoma cases. Drugs that inhibit BRAF are able to slow and often reverse the growth of melanoma tumors.
"With this technology, we are getting closer to the goal of a widely clinically applicable liquid biopsy, where we can sample cancer cells by a simple blood draw and understand the genes that allow them to grow," said Dr. Antoni Ribas, a professor of medicine in the division of hematology-oncology, a Jonsson Cancer Center member and one of Tseng's key collaborators. "With the NanoVelcro chips, we will be able to better personalize treatments to patients by giving the right treatment to stop what makes that particular cancer grow."
Dr. Roger Lo, another key Tseng collaborator and an assistant professor in UCLA's department of medicine, division of dermatology, and department of molecular and medical pharmacology, was also optimistic about the new method.
"This scientific advancement -- being able to capture the melanoma cells in transit in the blood and then perform genetic analysis on them -- will in principle allow us to track the genomic evolution of melanoma under BRAF-inhibitor therapy and understand better the development of drug resistance," said Lo, who is also a member of the Jonsson Cancer Center.
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The above story is reprinted from materials provided by University of California - Los Angeles. The original article was written by Shaun Mason.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/0FRgHxcuhiQ/130225092252.htm
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Famed 007 singer honors franchise's musical tradition during Sunday's (February 24) ceremony.
By Kevin P. Sullivan
Shirley Bassey performs at the 2013 Oscars
Photo: Mark Davis/ Getty Images
Source: http://www.mtv.com/news/articles/1702513/shirley-bassey-james-bond-oscars-tribute.jhtml
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Do you have any heroes? Most of us look up to or admire someone. Other people can inspire us, move us emotionally or just plain save our butts. But what is a hero?
In this Weekly Wisdom, Dean talks about some people who may or may not be an inspiration to you. Then he offers up something for you to think about. The hero may be hiding in plain sight in your life. Check this one out, it?s a keeper. PS, if you haven't voted on the Send Me Away content please cast your vote now!
Source: http://www.deangraziosi.com/content/weekly-wisdom-224-i-need-hero-or-do-i
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